Pellagra, a disease which is characterized by diarrhea, dermatitis, dementia, and finally, death (the four D’s), is believed to have been first described by Gasper Casal, a doctor in Asturias, Spain, in 1735. It was seen in southern Europe and the Mediterranean area for two centuries before it appeared in the United States.O Salutaris Hostia No.3 in F major (Elgar, Edward) Composition Year. 1880. Genre Categories. Sacred hymns; Hymns; Religious works; For mixed chorus, organ; Scores featuring mixed chorus; Scores featuring the organ; For …Pellagra is a systemic disease caused by vitamin B3 (niacin) deficiency. It is characterised by the 4 D’s — dermatitis, diarrhoea, dementia and, if untreated, death. The name …Pellagra is a form of malnutrition caused by a severe deficiency of niacin (also known as nicotinic acid or vitamin B3) in the diet. The disease affected thousands of Arkansans and other Southerners in the late nineteenth and early twentieth centuries. Symptoms of pellagra can include lack of energy, outbreaks of red splotches on the skin ...Symptoms of Pellagra. Dermatitis, dementia and diarrhea are the major symptoms associated with pellagra because a deficiency of niacin is highly noticeable in areas of the body where there are high rates of cell turnover, such as the skin or gastrointestinal tract. If untreated, it may cause a fourth D, which is death.Jan 20, 2021 · Pellagra is a clinical syndrome characterised by dermatitis, diarrhoea dementia and if untreated may result in death. A deficiency of niacin causes it. Pellagra was initially described by a Spanish Physician Gasper Casal. Previously nutritional deficiency was the leading and recognised cause of pellagra in the world. Some of the most common symptoms that are seen in people suffering from Pellagra would be diarrhoea, dementia, and dermatitis. This might be attributed to the fact that there is a niacin deficiency in the body of the person. This causes cell turnover and hence causes the gastrointestinal tract and the skin to have problems.A 38-year-old woman presented with bruising and pain of the lower extremities and dyspnea on exertion. She had had these symptoms for 3 weeks. She denied hematuria, melena, hematemesis, fever, or abdominal pain. Results of routine blood work showed a hemoglobin level of 6.4 g/dL (19 months earlier, this level was 15.8 g/dL).圖片來源：Wikipedia. 最近聽到有這麼一個網路謠言：玉米吃多了會得糙皮病（pellagra）。. 這個謠言讓我覺得相當驚訝，玉米的確與糙皮病有關，但中間沒有因果關係。. 怎麼說呢？. 我們先來看糙皮病。. 典型的糙皮病是因為飲食中缺乏維生素B 3 （菸鹼 …In 1912, he proposed the name "vitamine" for unidentified substances that were needed to prevent nutritional deficiency diseases, including beri-beri, scurvy, and pellagra. Indeed, he said that each of these diseases was caused by deficiency of a certain vitamine. This proposal and the coining of the name "vitamine" have been termed "a stroke ...Symptoms and Signs of Niacin Deficiency. Pellagra is characterized by skin, mucous membrane, central nervous system, and gastrointestinal symptoms. Advanced pellagra can cause a symmetric photosensitive rash, stomatitis, glossitis, diarrhea, and mental aberrations. Symptoms may appear alone or in combination.Pellagra is a form of malnutrition caused by a severe deficiency of niacin (also known as nicotinic acid or vitamin B3) in the diet. The disease affected thousands of Arkansans and other Southerners in the late nineteenth and early twentieth centuries. Symptoms of pellagra can include lack of energy, outbreaks of red splotches on the skin ...Pellagra is a disease caused by low levels of niacin, also known as vitamin B-3. It’s marked by dementia, diarrhea, and dermatitis, also known as “the three Ds”. If …The emergence of beri-beri had a mechanical basis; the introduction of milling, which prevented the rancidity of rice and wheat, also removed the essential vitamin B 1. The circumstances leading to the third deficiency disease was reliance on maize, without supplementing it with “protective” foods, such as meat, milk, and vegetables.Pellagra and the origin of a myth: evidence from European literature and folklore. - PMC. Journal List. J R Soc Med. v.90 (11); 1997 Nov. PMC1296679. As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health.Jan 20, 2021 · Pellagra is a clinical syndrome characterised by dermatitis, diarrhoea dementia and if untreated may result in death. A deficiency of niacin causes it. Pellagra was initially described by a Spanish Physician Gasper Casal. Previously nutritional deficiency was the leading and recognised cause of pellagra in the world. Pellagra is a nutritional wasting disease attributable to a combined deficiency of tryptophan and niacin (nicotinic acid). It is characterized clinically by four classic symptoms often referred to ...Pellagra is a systemic disease that results from severe vitamin B3 (Niacin) deficiency. Mild deficiency may go unnoticed, but a diet chronically low or without Niacin may result in …Hubungi dokter segera jika merasakan gejala pellagra. Komplikasi. Pencegahan. KOMPAS.com - Pellagra adalah penyakit yang disebabkan oleh rendahnya kadar niasin atau vitamin B-3. Kemunculan penyakit ini ditandai dengan demensia, diare, dan dermatitis. Jika tidak diobati, pellagra bisa berakibat fatal. Baca juga: Manfaat Vitamin B3 untuk Tubuh.Pellagra. Pellegra is a disease caused by a dietary deficiency of, or a failure to absorb, niacin (vitamin B 3) or the amino acid tryptophan, a precursor of niacin. First reported in 1735 by Don Gasper Casal, a Spanish physician, pellagra means "rough skin." Primary symptoms include the "3 Ds": dementia (mental symptoms), dermatitis (scaly …Apr 24, 2017 · Secondary pellagra is the result of improper absorption of the nutrient, whether as a whole or partially. This is observed with gastrointestinal diseases that do not accept the niacin. Other pellagra causes can be linked to a decrease or deficiency of amino acids tryptophan and lysine. Symptoms of Pellagra Pellagra and the origin of a myth: evidence from European literature and folklore. - PMC. Journal List. J R Soc Med. v.90 (11); 1997 Nov. PMC1296679. As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health.Niacin deficiency (causing pellagra) is uncommon in countries with low rates of food insecurity. Many people with niacin deficiency also have deficiencies of protein , riboflavin (a B vitamin), and vitamin B6 . A distinctive dark red rash appears on the hands, feet, calves, neck, and face, and the tongue and mouth turn dark red.Pellagra is a disease caused by low levels of niacin, also known as vitamin B-3. It’s marked by dementia, diarrhea, and dermatitis, also known as “the three Ds”. If …Pellagra is a disease that affects your digestive system, skin, and nerves, resulting in dermatitis, diarrhea, and mental disorders.The most common cause of pellagra is not having enough niacin (primary pellagra). Other causes of pellagra are associated with digestive disorders that reduce the absorption of niacin in your body. ...Define pellagra. pellagra synonyms, pellagra pronunciation, pellagra translation, English dictionary definition of pellagra. n. A disease caused by a deficiency of niacin and protein in the diet and characterized by skin eruptions, digestive and nervous system ...A condition caused by vitamin B3 deficiency resulting in pellagra rash, diarrhea, and dementia. Learn about preventative measures & treatment Learn about this condition caused by niacin deficiency and how to identify its symptoms, causes, and treatment options in …Pellagra, a nutritional deficiency disease caused by the lack of vitamin B3 (niacin) in the diet, is characterized by the four-d’s: dermatitis, diarrhea, dementia, and in some cases death. It is a global disease affecting places where the population diet is primarily maize-based. First described in Spain by Gasper Casal y Julian in 1735, it ...Pellagra is a disease caused by low levels of niacin, also known as vitamin B-3. It’s marked by dementia, diarrhea, and dermatitis, also known as “the three Ds”. If …Oct 17, 2018 · Diarrhea, dementia, dermatitis, and death are the signature 4 Ds of the now rare entity known as pellagra. Pellagra was once a national epidemic that baffled doctors and researchers. Between 1906 and 1940, approximately three million Americans developed pellagra, with 100,000 of these cases fatal (Rajakumar, 2000). Initially, the disease was ... Pellagra. Pellegra is a disease caused by a dietary deficiency of, or a failure to absorb, niacin (vitamin B 3) or the amino acid tryptophan, a precursor of niacin. First reported in 1735 by Don Gasper Casal, a Spanish physician, pellagra means "rough skin." Primary symptoms include the "3 Ds": dementia (mental symptoms), dermatitis (scaly …Mar 26, 2021 · Pellagra was never as prevalent in South Africa as in Europe, the USA and Egypt, where special hospitals for pellagrins were established. However, studies on urinary excretion of metabolites conducted in 1960s and 1970s suggested a high prevalence of subclinical (sub-pellagra) niacin deficiency, especially in previously disadvantaged Black ... Casál, 1762. Definition. This section has been translated automatically. Rare avitaminosis due to lack of vitamin B3 and possibly other factors of the B-complex (vitamin B6) with skin, intestinal and CNS disorders. Pellagra occurs when the diet consists mainly of maize or sorghum millet. The bound form of niacin (niacytin) present there cannot ...Hubungi dokter segera jika merasakan gejala pellagra. Komplikasi. Pencegahan. KOMPAS.com - Pellagra adalah penyakit yang disebabkan oleh rendahnya kadar niasin atau vitamin B-3. Kemunculan penyakit ini ditandai dengan demensia, diare, dan dermatitis. Jika tidak diobati, pellagra bisa berakibat fatal. Baca juga: Manfaat Vitamin B3 untuk Tubuh.Apr 24, 2017 · Secondary pellagra is the result of improper absorption of the nutrient, whether as a whole or partially. This is observed with gastrointestinal diseases that do not accept the niacin. Other pellagra causes can be linked to a decrease or deficiency of amino acids tryptophan and lysine. Symptoms of Pellagra Pellagra is a nutritional deficiency disease caused by a niacin deficiency and has recently received renewed attention, in part due to its appearance in refugees and displaced peoples ( Mason, 2002 see discussion in Box Feature 9.1 ). However, there are a number of reports of pellagra from historical contexts.Jan 18, 2021 · Pellagra is a disease that affects your digestive system, skin, and nerves, resulting in dermatitis, diarrhea, and mental disorders. The most common cause of pellagra is not having enough niacin (primary pellagra). Other causes of pellagra are associated with digestive disorders that reduce the absorption of niacin in your body. What is pellagra? Pellagra is a nutritional disorder caused by the deficiency of niacin, which is one of the vitamins in the vitamin B-complex group. The deficiency can occur as a result of poor intake or digestive …Episode 192: ℹ️ Adding an electric fireplace to your existing travel trailer or fifth wheel is now possible. In fact, most new models are equipped with elect...PELLAGRA C.J. Bates, in Encyclopedia of Human Nutrition (Second Edition), 2005Complex Causation Although pellagra in dogs and humans usually responds well to supplements of pure niacin, there are several further strands to the story that complicate the idea that all the characteristics and manifestations of pellagra can be explained as the result of a simple …TAKE YOUR STYLE QUIZ NOW >. Ellegra is an online personal styling service. Get your Ellegra style box: 5 items hand-picked by your personal stylist and only pay for what you keep. We style every shape and size from UK6 to UK28! Try it now. Nguyên nhân gây bệnh Pellagra: Ăn ngô hoặc lúa miến nguyên chất, không chế biến. Chỉ ăn ngô và ăn lúa miến mà không ăn thêm các loại ngũ cốc khác. Rối loạn hấp thụ của cơ quan tiêu hóa do thiếu vitamin PP và các vitamin nhóm B khác như B1, B2, B6. Nhiều chị em muốn giảm cân ... Bệnh Pellagra thường xảy ra khi mức niacin (vitamin B3) trong cơ thể thấp. Đặc trưng của bệnh gồm mất trí nhớ, tiêu chảy, viêm da. Cùng eLib.VN tìm hiểu về triệu chứng, nguyên nhân và cách điều trị của bệnh lý này qua bài viết dưới đây.. Dermatitis related to pellagra usually causes a rash on the face, lips, feet, or hands. In some people, dermatitis forms around the neck, a symptom known as Casal necklace. Primary pellagra is caused by diets low in niacin or tryptophan. Tryptophan can be converted to niacin in the body, so not getting enough can cause niacin deficiency. Niacin (also known as vitamin B3) is one of the water-soluble B vitamins. Niacin is the generic name for nicotinic acid (pyridine-3-carboxylic acid), nicotinamide (niacinamide or pyridine-3-carboxamide), and related derivatives, such as nicotinamide riboside [ 1-3 ]. Niacin is naturally present in many foods, added to some food products, and ... pellagra, nutritional disorder caused by a dietary deficiency of niacin (also called nicotinic acid) or a failure of the body to absorb this vitamin or the amino acid …The Westminster Cathedral Choir, under the direction of Dr R E Terry, sing "O Salutaris Hostia" by Sir Edward Elgar, recorded in London in October 1911. His ... Some of the most common symptoms that are seen in people suffering from Pellagra would be diarrhoea, dementia, and dermatitis. This might be attributed to the fact that there is a niacin deficiency in the body of the person. This causes cell turnover and hence causes the gastrointestinal tract and the skin to have problems. 每日投與兩次60 公絲與每日投與兩次30 公絲相較,並無較大的益處。. 而且兒童患者投與30mg fexofenadine hydrochloride和成年患者投予60 公絲的劑量結果相似( 見臨床藥理學)。. 在三項針對845 位6 個月到5 歲過敏性鼻炎兒童患者的臨床安全性試驗中,進行每日投予兩次15 ...Pellagra symptoms are resolved by niacin, but aggravated mainly by vitamin B 6. Alcohol dependence can induce or aggravate pellagra by inducing malnutrition, gastrointestinal disturbances and B vitamin deficiencies, inhibiting the conversion of Trp to niacin and promoting the accumulation of 5-ALA and porphyrins.What is pellagra? Pellagra is a nutritional disorder caused by the deficiency of niacin, which is one of the vitamins in the vitamin B-complex group. The deficiency can occur as a result of poor intake or digestive …Bệnh Pellagra thường xảy ra khi mức niacin (vitamin B3) trong cơ thể thấp. Đặc trưng của bệnh gồm mất trí nhớ, tiêu chảy, viêm da. Cùng eLib.VN tìm hiểu về triệu chứng, nguyên nhân và cách điều trị của bệnh lý này qua bài viết dưới đây.Pellagra is a nutritional wasting disease attributable to a combined deficiency of tryptophan and niacin (nicotinic acid). It is characterized clinically by four classic symptoms often referred to ... Niacin deficiency (causing pellagra) is uncommon in countries with low rates of food insecurity. Many people with niacin deficiency also have deficiencies of protein , riboflavin (a B vitamin), and vitamin B6 . A distinctive dark red rash appears on the hands, feet, calves, neck, and face, and the tongue and mouth turn dark red. Pellagra defines systemic disease as resulting from a marked cellular deficiency of niacin. It is characterized by 4 "D's": diarrhea, dermatitis, dementia, and death. Diagnosis of pellagra is difficult in the absence of the skin lesions, and is often facilitated by the presence of characteristic ones. The dermatitis begins as an erythema.May 13, 2022 · Practice Essentials. Pellagra is clinically manifested by the 4 D' s: photosensitive dermatitis, diarrhea, dementia, and death. This is the only photosensitivity syndrome where death is included as a cardinal clinical feature. [ 1] The full tetrad of symptoms is usually not well developed in infants and children. May 3, 2019 · Pellagra is caused by cellular deficiency of niacin or its precursor amino acid, tryptophan. Isoniazid preventive therapy (IPT) is the administration of isoniazid (INH) to latent tuberculosis (TB) infection affected people preventing advancement to active TB disease. Although potentially life-saving for human immunodeficiency virus (HIV ... Mar 26, 2021 · Pellagra was never as prevalent in South Africa as in Europe, the USA and Egypt, where special hospitals for pellagrins were established. However, studies on urinary excretion of metabolites conducted in 1960s and 1970s suggested a high prevalence of subclinical (sub-pellagra) niacin deficiency, especially in previously disadvantaged Black ... Pellagra is a metabolic disease caused by the insufficiency of vitamin B3 (niacin) and amino acid tryptophan. In hard tissues, this insufficiency is demonstrated as extensive alveolar bone loss ...Approach Considerations. Patients with acute cases of pellagra require bed rest during the initial phase of treatment. Patients with severe glossitis require a liquid or a soft solid diet to overcome the dysphagia. Various high-calorie drinks rich in protein and B vitamins (including niacin) are recommended. Topical management of skin lesions ...成份 2015-01-21 推動負責任的自我藥療政策說明. 艾來60公絲錠劑 ALLEGRA 60MG TABLETS / 緩解成人及六歲以上兒童的季節性過敏性鼻炎及慢性自發性蕁痲疹相關症狀 …A diagnosis of pellagra was made on the basis of the characteristics of his rash, presence of diarrhea, cognitive impairment, history of alcoholism, and poor nutrition. No definitive laboratory test exists for the diagnosis of pellagra. Upper GI endoscopy revealed erosive esophagitis and duodenitis consistent with mucosal inflammation.艾來錠180公絲 ALLEGRA TABLETS 180MG / 緩解成人及6歲以上兒童的季節性過敏性鼻炎及慢性自發性蕁麻疹相關症狀。 / 藥要看提供簡單的介面檢索國內有註冊登記的藥品 pellagra: [noun] a disease marked by dermatitis, gastrointestinal disorders, and mental disturbances and associated with a diet deficient in niacin. Mar 13, 2019 · Pellagra is classically described as the 4 D’s in order of symptoms starting: diarrhea (watery, but may contain pus or blood), dermatitis, dementia, death. Three 3 P’s also apply: photosensitive, painful, pruritic. Pellagra is the clinical manifestation of Vitamin B3 (niacin) deficiency. Early cutaneous findings, like many skin diseases ... Pellagra (which means "rough skin" from the Italian pelle agra) is due to a niacin deficiency or deficiency of the niacin precursor tryptophan. It is also referred to as mal del sole. Pellagra is a condition hallmarked by a symptom complex of the "4 Ds:" dermatitis (photosensitive rash), dementia, diarrhea, and death.Pellagra is a vitamin disorder caused by deficiency in vitamin B3, also called niacin. It is a multi-systemic disorder that most commonly involves skin, nervous system, …A diagnosis of pellagra was made on the basis of the characteristics of his rash, presence of diarrhea, cognitive impairment, history of alcoholism, and poor nutrition. No definitive laboratory test exists for the diagnosis of pellagra. Upper GI endoscopy revealed erosive esophagitis and duodenitis consistent with mucosal inflammation.Niacin, or vitamin B-3, is essential for preventing pellagra, the symptoms of which include skin problems, diarrhea, and dementia. It may have some use in medicine, but consuming too much can lead ...TAKE YOUR STYLE QUIZ NOW >. Ellegra is an online personal styling service. Get your Ellegra style box: 5 items hand-picked by your personal stylist and only pay for what you …Pellagra is a nutritional disease due to deficiency of the vitamin niacin and the essential amino acid tryptophan. The clinical features of pellagra are dermatitis, diarrhea, and …May 10, 2019 · Pellagra is a deficiency in vitamin B3 or niacin. First identified as a nutritional disease in Spain in 1735 by Don Gaspar Casal, Pellagra was originally known as mal de la rosa due to its characteristic symptom: red, rough skin. In 1914, Joseph Goldberger began studying the root of the problem. Mar 21, 2017 · A skin rash called “pellagra” is a common symptom. It usually results from exposure to sunlight. It’s an intermittent red and scaly rash that typically appears over your face, neck, hands ... Pellagra is a vitamin disorder caused by deficiency in vitamin B3, also called niacin. It is a multi-systemic disorder that most commonly involves skin, nervous system, and gastrointestinal tract. Indeed, pellagra is often said to consist of “the four Ds”: dementia, diarrhea, dermatitis, and death. Nowadays it is not a very common disease in developed countries, and …Pellagra is a nutritional disorder due to deficiency of vitamin B3 (niacin) which is characterized by dermatitis, dementia, diarrhea, and death. The most common site of dermatitis in pellagra is the Casal necklace; however, in this case, the presentation of dermatitis is in unusual sites. Therefore, mucocutaneous signs play a major role in …Jul 25, 2023 · Niacin or vitamin B3 are generic terms for nicotinic acid and nicotinamide (niacinamide). Niacin was initially referred to as the anti-black tongue factor due to niacin's effect on dogs.[1] In humans, niacin was discovered through the niacin deficiency condition pellagra. In the 1700s, pellagra first appeared in Italy, and the name translates into "pella," meaning skin, and "agra," meaning ... 藥品使用指導單 艾來®錠(Allegra®60mg) 藥品成分名 Fexofenadine 藥品外觀 淡紅橙，橢圓形，錠劑；大小：1.22公分；標記：[06][特殊標記] 作用 艾來®錠為第二代抗組織氨藥物 …Halodoc, Jakarta - Pellagra adalah suatu penyakit sistemik yang disebabkan oleh kekurangan yang parah vitamin B3 atau niacin. Ketika kekurangan vitamin B3 tersebut ringan, mungkin tidak diketahui adanya masalah. Namun jika terjadi kekurangan niacin dalam jangka waktu yang lama atau diet tanpa kandungan niacin, maka dapat menyebabkan munculnya ...May 13, 2022 · Ensure that the patient has a balanced diet that is rich in protein and niacin. The topical treatment of skin lesions with topical emollients may reduce discomfort. Pellagra is clinically manifested by the 4 D' s: photosensitive dermatitis, diarrhea, dementia, and death. The full tetrad of symptoms is usually not well developed in infants and ... Pellagra was not uncommon in the early 20th century among individuals living in poverty in the southern United States and parts of Europe whose limited diets consisted mainly of corn [2,3]. The World Health Organization recommends treating pellagra with 300 mg/day nicotinamide in divided doses for 3–4 weeks along with a B-complex or yeast product to treat likely …Allegra Cole World. @AllegraCole_. ·. Feb 3. 2002 vs 2022. I will always be evolving, growing, changing. This is what life is all about and I’m excited to see where I grow to …Pellagra is a complex systemic disease resulting from inadequate dietary intake of coenzyme precursors nicotinamide and tryptophan. Improved nutritional habits in most developed economies have led to a decrease in clinicians' and researchers' attention to this condition and its pathophysiological bases, although new cases of pellagra have recently …Sep 20, 2004 · Pellagra, a disease caused by a dietary deficiency in vitamin B (niacin), was seen in the southern United States after the Civil War (1861-65). In the early 1900s it was thought to be an infectious disease, but studies conducted by public health physician Joseph Goldberger at the Milledgeville State Hospital (later Central State Hospital) in […] Joseph Goldberger's research on the prevention of pellagra. Pellagra was first identified among Spanish peasants by Don Gaspar Casal in 1735. A loathsome skin disease, it was called ‘mal de la rosa’ and often mistaken for leprosy. Pellagra has sometimes been called the disease of the four Ds – dermatitis, diarrhoea, dementia and death. Pellagra is a nutrition deficiency disease, associated with niacin deficiency. The symptoms of pellagra are referred to as the three D’s, namely, dermatitis, diarrhoea and dementia, referring to skin, gastrointestinal and neuropsychiatric symptoms, respectively. How is Pellagra Treated? Oral supplementation of niacin can help control the signs and symptoms, reverse the condition, and correct the deficiency situation arising from Pellagra. A diet with adequate calories rich in meat, milk, peanuts, green leafy vegetables (such as spinach and broccoli), and whole grains is recommendedPellagra is a vitamin disorder caused by deficiency in vitamin B3, also called niacin. It is a multi-systemic disorder that most commonly involves skin, nervous system, and gastrointestinal tract. Indeed, pellagra is often said to consist of “the four Ds”: dementia, diarrhea, dermatitis, and death. Nowadays it is not a very common disease in developed countries, and …Who is Pellagra? Pellagra causes delusions or mental confusion, diarrhea, weakness, loss of appetite, pain in the abdomen, inflamed mucous membranes, and scaly skin sores, but the band sounds pretty good. Yeah, it’s a nasty disease, and very well may be the origin of zombies in the legends and lore of pirates and other riders of the sea.A pellagra (pelle agra = durva bőr) a niacin (B 3 -vitamin) hiánya okozta betegség. Tüneteit először Casal állapította meg 1735-ben. A betegség előfordulása a későbbiekben is gyakori volt minden olyan területen, ahol az egyik fő és szinte kizárólagos táplálékot a kukorica jelentette. A hiánybetegség manapság már ... Pellagra. Pellagra is a systemic disease that results from severe vitamin B3 (Niacin) deficiency. Mild deficiency may go unnoticed, but a diet chronically low or without Niacin may result in the 4 D’s: diarrhea, dermatitis, dementia, and possibly even death. Usually diarrhea will occur before the other D’s. Noun [ edit] pellagra ( countable and uncountable, plural pellagras) ( pathology) A disease characterised by skin lesions and mental confusion, primarily caused by a niacin deficiency. [from 19th c.] 1997, Roy Porter, The Greatest Benefit to Mankind, Folio Society, published 2016, page 531: In 1755 the French physician Gaspar Casal (1680–1759 ... ---1